Senior Scientist – Biotransformation
Company: Experis
Location: Groton
Posted on: July 2, 2025
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Job Description:
Senior Scientist – Biotransformation 18 month engagement Our
client in Groton, CT, a leader in drug discovery and development,
is seeking a Senior Scientist – Biotransformation to join their
Pharmacokinetics, Dynamics, and Metabolism (PDM) team focused on
small molecule drug discovery. In this role, you will support and
guide the understanding of human drug metabolism through curation
and interpretation of large-scale experimental metabolite ID data
to drive predictive modeling efforts to maximize the value of the
curated data. This is a long-term engagement offering the
opportunity to contribute to cutting-edge research with real-world
therapeutic impact. Key Responsibilities: Analyze high-resolution
mass spectrometry data (HRMS), including MS2 fragmentation for
small molecule structural elucidation. Interpret metabolic pathways
using knowledge of human drug-metabolizing enzymes and common
metabolite types. Collaborate with computational ADME staff to
develop and apply computational models to support biotransformation
research in small molecule drug discovery. Leverage spreadsheets
and/or BI tools (e.g., Excel, Spotfire, Tableau, JMP) for data
visualization and analysis. Apply statistical methods to derive
insights from complex datasets. Contribute to internal discussions
and presentations of data insights and recommendations. Required
Qualifications: PhD in a relevant field (e.g., Pharmaceutical
Sciences, Chemistry, Biochemistry) or MS with 2 years of relevant
industry experience. Strong understanding of: Human drug metabolism
enzymes Common metabolite structures General organic chemistry
Experimental systems for assaying metabolism Demonstrated
experience analyzing HRMS data, including MS2 fragmentation
patterns. Keen interest in computational approaches and data-driven
science. Proficiency with data visualization tools (Excel,
Spotfire, Tableau, JMP). Solid foundation in statistical principles
(through coursework or practical application). Strong analytical
and problem-solving skills. Preferred Qualifications: Experience
with automated analysis of HPLC-HRMS or HPLC-UV-HRMS datasets.
Familiarity with HPLC-UV data analysis. Proficiency in at least one
programming language (e.g., Python, R). Why Join Us? Be part of a
collaborative and innovative team at the intersection of drug
metabolism and data science. Contribute directly to projects that
advance therapeutic development. Enjoy opportunities for scientific
growth and long-term professional engagement. About ManpowerGroup,
Parent Company of: Manpower, Experis, Talent Solutions, and
Jefferson Wells ManpowerGroup® (NYSE: MAN), the leading global
workforce solutions company, helps organizations transform in a
fast-changing world of work by sourcing, assessing, developing, and
managing the talent that enables them to win. We develop innovative
solutions for hundreds of thousands of organizations every year,
providing them with skilled talent while finding meaningful,
sustainable employment for millions of people across a wide range
of industries and skills. Our expert family of brands – Manpower,
Experis, Talent Solutions, and Jefferson Wells – creates
substantial value for candidates and clients across more than 75
countries and territories and has done so for over 70 years. We are
recognized consistently for our diversity - as a best place to work
for Women, Inclusion, Equality and Disability and in 2022
ManpowerGroup was named one of the World's Most Ethical Companies
for the 13th year - all confirming our position as the brand of
choice for in-demand talent.
Keywords: Experis, New England , Senior Scientist – Biotransformation, Science, Research & Development , Groton, Northeast
