Principal Scientist/Senior Principal Scientist, Project Team Toxicologist

Company: Boehringer Ingelheim
Location: Ridgefield
Posted on: July 23, 2021

Job Description:

Description:

As a primary responsibility, this job has oversight for the design and execution of nonclinical safety programs to support the development of drug candidates from discovery to market authorization.  The incumbent will be highly motivated and independently manage a portfolio of projects in multiple therapeutic areas and modalities including small molecules, monoclonal antibody-based biotherapeutics, oligonucleotides, viral, and gene therapies.  As the primary interface between global project teams and Nonclinical Drug Safety, the incumbent is responsible for developing nonclinical safety strategies that support the clinical development plan in oncology and non-oncology indications.  The NDS team member will be the primary interface with global health authorities and will consolidate safety data from nonclinical studies into regulatory submissions as needed. In addition integrated safety assessments may also be presented to senior management at milestone review meetings.  The incumbent may also serve as, or interface closely with, Therapeutic Area Leads responsible for knowledge of a broad therapeutic area and related internal portfolio.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities\:

• Independently designs and performs scientific experiments with a predefined goal including developing new methodologies; Protocols and or test procedures that contribute to core group/research goals and reflect expert knowledge; Direct and oversee experimental design and results of technicians and junior level scientists.
• Contributes to defining R&D team goals and collaborates with scientists within and outside functional area in achieving them; Assumes departmental responsibility for either projects or has ability to participate as representative on multiple project teams and contribute to defining expertise-related aspects of overall program goals.
• Prepares clear technical reports, publications and oral presentations. Independently communicate results in the form of reports and or presentations; Deliver updates to senior level management in context of overall project goals.
• Demonstrates an expertise in a specific project-relevant area or technology; Provide guidance and expertise to advance specific projects or evaluate and propose new technologies and concepts in support of multiple projects; Develops broad knowledge in field of expertise, including the ability to interpret current literature relevant to R&D projects, and visibility outside of functional area.
• Complies with all applicable regulations; Ensures that work performed in area of responsibility is conducted in a safe and compliant manner; Maintains proper records in accordance with SOPs, appropriate guidance and policies.
• Contributes to departmental administration; Demonstrates fiscal responsibility with respect to cost of experiments, technology, external collaborations, and travel.

Principal Scientist Requirements\:

• PhD, DVM, MD or equivalent degree from an accredited institution with at least 5+ years related experience, or relevant MS degree and at least 10+ years related experience.  DABT certification is desirable.
• Demonstrates a broad knowledge in field of toxicology.  Candidate possesses practical knowledge of pharmaceutical toxicology including approaches to discovery toxicology, relevant regulatory guidelines and preparation of submission documentation.
• Demonstrated knowledge of specific platforms (e.g. monoclonal antibodies, oligonucleotides, viral, and gene based therapies) or therapeutic areas is desirable.
• Demonstrated ability to work effectively in a team environment.
• Excellent ability to communicate effectively both orally and in writing in an interdisciplinary environment.

Sr. Principal Scientist Requirements\:

• PhD or equivalent degree from an accredited institution in the areas Toxicology or Pharmacology, with at least 8+ years related experience.  DABT certification is desirable.
• Demonstrates a broad knowledge in field of toxicology.  Candidate possesses practical knowledge of pharmaceutical toxicology including approaches to discovery toxicology, relevant regulatory guidelines and preparation of submission documentation.
• Knowledge of specific platforms (e.g. viral and gene therapies, monoclonal antibodies, and oligonucleotides) or therapeutic areas is highly desirable.
• Routinely apply optimal tactical practices that impact projects, filings, and other disciplines. 
• Enable team to deliver milestones by defining research and development project goals; ensuring execution of the plan and that the team has sufficient resources.
• Demonstrates ability to work effectively in a team environment.
• Excellent ability to communicate effectively both orally and in writing in an interdisciplinary environment.

Eligibility Requirements\:

• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older

Who We Are\:

At Boehringer Ingelheim we create value through innovation with one clear goal\: to improve the lives of patients. We develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company we focus on long term performance. We are powered by 50.000 employees globally who nurture a diverse, collaborative and inclusive culture. Learning and development for all employees is key because 

your growth is our growth.

Want to learn more?  Visit boehringer-ingelheim.com and join us in our effort to make more health.

Boehringer Ingelheim, including Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Animal Health USA Inc., Boehringer Ingelheim Animal Health Puerto Rico LLC, and Boehringer Ingelheim Fremont, Inc. is an equal opportunity and affirmative action employer committed to a culturally diverse workforce.  All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender identity or expression; affectional or sexual orientation; disability; veteran or military status, including protected veteran status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by applicable law.

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Keywords: Boehringer Ingelheim, New England , Principal Scientist/Senior Principal Scientist, Project Team Toxicologist, Other , Ridgefield, Northeast